Nootropics

Glycine vs L-Theanine: The Night vs The Day

Both Glycine and L-Theanine are amino acids that promote "calm." But they are used at opposite times of the day.

L-Theanine is the "Daytime Calm." It helps you focus at work. Glycine is the "Nighttime Cool." It helps you drop into deep sleep.

Feature Glycine L-Theanine
Primary Time Before Bed Morning / Afternoon
Mechanism Lowers Body Temp Alpha Brain Waves
Taste Sweet Umami / Savory
Drowsiness Yes (at 3g+) No

Mechanisms: Cooling vs Tuning

Glycine: The Cool Down

Glycine triggers peripheral vasodilation (widening of blood vessels in skin). This dumps heat from your core.

A dropping core temperature is the biological signal for the brain to release melatonin and enter SWS (Slow Wave Sleep).

L-Theanine: The Frequency Tuner

L-Theanine crosses the blood-brain barrier and increases Alpha activity (8-13 Hz). This is a state of "wakeful relaxation."

It quiets the noise but keeps the light on. Ideal for meditation or flow states.

Which One Matches Your Goal?

For Refreshing Sleep

Winner: Glycine.

L-Theanine helps you fall asleep if your mind is racing, but Glycine actually improves the *quality* of the sleep cycles. It reduces grogginess the next day.

For Caffeine Jitters

Winner: L-Theanine.

Glycine won't help with coffee jitters. L-Theanine is the perfect antidote to caffeine side effects.

The Verdict

Choose Glycine if: You want to wake up feeling more rested or need to lower your body temperature at night.

Choose L-Theanine if: You want mental clarity, focus, and calm during the day.