Melatonin vs Oleamide: Signaling vs Sedating

Most people take Melatonin thinking it is a sedative. It is not. It is a hormone that tells your body "it is dark now."

Oleamide, on the other hand, mimics the buildup of sleep debt. It makes you feel physically exhausted and ready to crash.

Mechanisms: Rhythm vs Debt

Melatonin: The Conductor

Melatonin is produced by the pineal gland when blue light hits the retina drops. Taking it supplements this signal. It helps you fall asleep *faster* (latency) but doesn't necessarily keep you asleep.

Oleamide: The Hammer

Oleamide acts on the cannabinoid and serotonin systems. It increases the "drive" to sleep. Even if you are wide awake and stressed, Oleamide can force a shutdown.

Which One Matches Your Goal?

For Jet Lag

Winner: Melatonin.

Nothing beats Melatonin for adjusting to a new time zone. Oleamide will just make you tired at the wrong time.

For Shift Work / Insomnia

Winner: Oleamide.

If you need to sleep during the day or have severe insomnia where Melatonin doesn't work, Oleamide is the stronger option.

The Verdict

Choose Melatonin if: You just need a nudge to fall asleep or are fixing your schedule.

Choose Oleamide if: You need a heavy-duty sleep aid and are willing to risk some morning grogginess.